January 28, 2023

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Molnupravir removes the active Covit-19 virus in three days

Molnupravir
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Covit-19 is an oral anti-mollusk drug that eliminates the highly contagious SARS-Cov-2 virus on the third day of treatment. This is according to a study presented at the European Congress of Clinical Microbiology and Infectious Diseases (Eccmid).

However, many patients who received the placebo took up to five days to remove it. And in some cases, longer. This was pointed out in a study conducted by the pharmaceutical company MSD, the brand name of the drug manufacturer Merck.

Molnupravir

The MOVe-OUT stage 2/3 test has already confirmed the superiority of the drug over placebo for adults who are admitted to the hospital with mild to moderate covit-19 and risk of progressing to severe disease if treatment is started within five days of the onset of symptoms. . According to The New England Journal of Medicine.

World Health Organization (WHO)who) Announced on the 3rd that this antiviral drug would be added to the list of recommended treatments against Govit-19. It is also approved for emergency use in countries such as the United States, the United Kingdom, Australia and Japan.

The study will be submitted to Eccmid next week. But he said in a statement today that participants underwent PCR tests to determine SARS-CoV-2 RNA virus loads from nasopharyngeal swabs collected on days 1 (initiation), 3, 5 (end of visit) treatment), and 10, 15 days. And 29.

On the third day of treatment, none of the 92 participants receiving molnupravir were diagnosed with SARS-CoV-2 infection. Compared with 21.8% (20 out of 96) of the participants who took the placebo.

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Five days later, those treated with the drug were virus-free, with 2.2% still being diagnosed in the other group. Finally, on the tenth day, none of the participants in either group were in favor of the virus.

This analysis of the final data of the MOVe-OUT test confirms previous observations that treating Molnubira twice daily “creates a faster breakdown in viral RNA and eliminates the infecting virus more quickly than placebo,” said Julie Streisky. M.S.D.

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